I use ZBrush and 8 cubes to create a hand. I begin by sculpting the basic shape of the palm with the first cube and create the arm with the second cube. I move on to the fingers with a cube extruded into a small box shape. A fourth cube is used for the stub of the thumb. I duplicate the finger 3 times for the other fingers making sure to bend them slightly towards the middle finger. Finally, I add another box to create the thumb. The sculpt is then reprojected onto a base mesh I created.